Dental Caries is a major public health concern worldwide, affecting more than 80% of the population alive in the world today. Its impact on individuals and communitiesï¿½as a result of pain and suffering, impairment of function, and reduced quality of lifeï¿½is considerable . Dental caries initiation and progression is dependent upon four independent factors as illustrated in Figure 1. Its incidence can be prevented by modification of one of the four factors mentioned in Figure 1. However due to limited access to professional care, oral hygiene education, health status, huge population and economic limitations the total preventive programs for dental carries cannot be fully successful. This lead to explore the alternate ways to combat this complex situation, one of such promising concept is bio-engineering modified S. Mutans.
Dr. Rajiv Saini